New Hope For The Wretched

The SARS-CoV-2 virus is highly contagious but the current dominant strains are not very lethal. Its much rarer cousin in the betacoronavirus family of pathogens, MERS-CoV, is highly lethal but not very contagious. Now imagine a blend of the two—a respiratory virus with the most dangerous qualities of both. Contagious and lethal.

Stop, I'm getting excited already.

It’s a real risk, according to a new study from China. And it’s a strong argument for a new, more widely effective vaccine. Different viruses from the closely related families can combine through a process called “recombination” and produce hybrids called “recombinants.” This recombination requires the viruses to share an infection mechanism. For the first time, a team of scientists in China has identified the mechanism by which SARS and MERS could combine—by entering human cells via colocated receptors. Basically, the cells’ entry points for external molecules.

If a single person ever catches SARS and MERS at the same time through neighboring receptors and the two viruses combine, we could have a whole new pandemic on our hands—one that could be far worse than the current COVID-19 pandemic.

Can't always count on nature to come through, of course, but it does give this reporter a reason to live.

[Daily Beast. Try incognito mode.]